Diabetes: Are high blood glucose levels an effect rather than the cause of the disease?

Insulin resistance and elevated blood glucose levels are considered to be the cause of type 2 diabetes. However, scientists have now provided evidence that things might be completely different. They showed in flies that elevated levels of the metabolite MG (methylglyoxal) cause the typical diabetic disturbances of the metabolism and lead to insulin resistance, obesity and elevated blood sugar levels.
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